Search results for "Fluorescence cellular imaging"

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Cellular imaging using BODIPY-, pyrene- and phthalocyanine-based conjugates

2017

International audience; Fluorescent Probes aimed at absorbing in the blue/green region of the spectrum and emitting in the green/red have been synthesized (as the form of dyads-pentads), studied by spectrofluorimetry, and used for cellular imaging. The synthesis of phthalocyanine-pyrene 1 was achieved by cyclotetramerization of pyrenyldicyanobenzene, whereas phthalocyanine-BODIPY 2c was synthesized by Sonogashira coupling between tetraiodophthalocyanine and meso-alkynylBODIPY. The standard four-steps BODIPY synthesis was applied to the BODIPY-pyrene dyad 3 starting from pyrenecarbaldehyde and dimethylpyrrole. H-1, C-13, F-19, (BNMR)-B-11, ICP, MS, and UV/Vis spectroscopic analyses demonstra…

Boron CompoundsIndolesFluorescence cellular imagingClinical BiochemistryPharmaceutical ScienceSonogashira couplingIsoindoles010402 general chemistryPhotochemistry01 natural sciencesBiochemistrylaw.inventionPhthalocyanine-BODIPYMicechemistry.chemical_compoundDyad/pentad synthesesConfocal microscopylawBODIPY-pyreneDyads[SDV.IDA]Life Sciences [q-bio]/Food engineeringDrug DiscoveryTumor Cells CulturedAnimalsMelanoma-cells[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPhthalocyanine-pyreneMelanoma[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular BiologyMolecular BiologyFluorescent DyesPyrenesMolecular Structure010405 organic chemistryChemistry[CHIM.ORGA]Chemical Sciences/Organic chemistryOrganic Chemistry[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringFluorescenceAcceptorSpectral properties0104 chemical sciencesMembraneEnergy transferPhthalocyanineMolecular MedicinePyreneBODIPYSpectrofluorimetry

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